Drug Topics December 9, 2025
Key Takeaways
- Overdose deaths are projected to decrease by 34% in 2025, with fentanyl as the primary driver of fatalities.
- Methadone, naltrexone, and buprenorphine have distinct pharmacological profiles, influencing individualized patient care.
- Microdosing strategies are used to manage fentanyl-driven inductions, avoiding precipitated withdrawal.
- Long-acting injectables offer clinical and adherence benefits, reducing the need for daily compliance and minimizing diversion risks.
Progress against the opioid crisis shows promise, with overdose deaths declining, and pharmacists play a crucial role in life-saving medication strategies.
The battle against the opioid crisis is seeing cautious progress, with drug overdose deaths reaching approximately 107,000 in 2023. This is projected to be the lowest level since 2019 after falling 34% in 2025, according to Lawrence...
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