STAT March 28, 2024
Lisa Shah

Oprah Winfrey, true to form, is forcing America to yet again grapple with a complex topic: weight loss. Her full-throated endorsement on national television last week for using GLP-1 drugs like Ozempic and Wegovy to treat obesity has opened the door for an important conversation about the use of these drugs for people struggling with their weight.

As a physician focused on obesity and metabolic disorders, I was troubled by Oprah’s support for these drugs. The show was framed as news, but sounded to me more like an hour-long infomercial. When it comes to GLP-1 drugs, there are some things prescribers know, more we’re just beginning to know, and plenty we don’t know yet.

People deserve to be happy and...

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