STAT July 12, 2024
Health care is undergoing an important and well-needed shift from a one-size-fits-all approach to more personalized, precise, patient-focused care. A similar approach needs to be implemented at scale for clinical trials.
Over the past decade, precision medicine has evolved from merely creating personalized treatment plans and delivery methods to being integral throughout the entire drug development process.
One of the most dramatic areas in which this change is occurring is the clinical trial phase of drug development. Whereas traditional clinical trials follow rigid, predetermined protocols, adaptive clinical trials use the data accumulating from participants to inform decisions made throughout the trial. This may include suggesting modifications, dropping poorly performing arms, and answering questions to optimize and enhance outcomes. By enabling...
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