HIT Consultant November 7, 2025
Fred Pennic

What You Should Know:

Onchilles Pharma, a private biotech company pioneering next-generation cytotoxic therapeutics announced the publication of foundational preclinical data in the peer-reviewed journal Cell Reports Medicine, the close of a $25M Series A1 financing round.

– In addition, the company appointed Dr. Thomas A. Buchholz as a clinical advisor. The funding brings the total raised in Series A financing to $40M.

Foundational Preclinical Data Validates Cancer-Selective Mechanism

The published study provides the most comprehensive validation to date of the ELANE pathway as a cancer-selective, immune-activating mechanism. Onchilles’ lead drug candidate, N17350, is a tumor-directed biologic that leverages this pathway to selectively kill cancer cells while sparing healthy tissue and activating a systemic immune response.

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Topics: Biotechnology, Investments, Pharma / Biotech, Trends
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