MedPage Today October 30, 2024
David Fajgenbaum, MD, MBA, MSc, and Reece Williams

— COVID highlighted the untapped potential of existing treatments

As COVID-19 rapidly evolved from an outbreak to a pandemic, researchers, clinicians, governments, and the public were all desperately seeking solutions. In the setting of this urgency, drug repurposing emerged as a powerful strategy for identifying potential treatments — utilizing medications already available on pharmacy shelves around the world.

Some proved effective, while others did not. In the end, it was the lesser-known repurposed drugs that received far less attention that ended up saving the most lives: dexamethasone, tocilizumab (Actemra), and baricitinib (Olumiant). These drugs quietly saved, and continue to save, countless lives, demonstrating the immense potential of repurposing to unlock additional life-saving uses of existing drugs.

We believe that the...

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