Medscape February 21, 2025
TOPLINE:
A nutrient pattern rich in magnesium, hydroxybenzaldehydes, stilbenes, dihydroflavonols, vitamin B, lignans, tyrosols, and proanthocyanidins is associated with 15% lower odds of depressive symptomatology (DS) in older adults, a 15-year study showed.
METHODOLOGY:
- Researchers analysed data of 1063 participants (mean age, 75.6 years; 56.6% women) from the French Three-City cohort study from 2001 to 2018.
- Nutrient intake was assessed using 24-hour dietary recall interviews. Principal component analysis was performed on 40 selected nutrients, including 21 polyphenols, three carotenoids, five fatty acids, nine vitamins, and two minerals.
- DS was evaluated on the basis of a Center for Epidemiologic Studies-Depression score > 16 and/or antidepressant use.
- The analysis controlled for sociodemographic and lifestyle factors. The median follow-up duration was 11.5...
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