Medscape October 8, 2024
Michael van den Heuvel

This year, the Royal Swedish Academy of Sciences is honoring two US researchers with the Nobel Prize in Medicine for the discovery of a fundamental principle of how gene activity is regulated. Victor Ambros, PhD, a researcher at the University of Massachusetts Chan Medical School in Worcester, Massachusetts, and Gary Ruvkun, PhD, professor of genetics at Harvard Medical School in Boston, discovered microRNAs, a new class of RNA molecules.

“Their groundbreaking discovery in the small worm Caenorhabditis elegans revealed a completely new principle of gene regulation. This turned out to be essential for multicellular organisms, including humans,” said the Nobel Assembly in a statement.

Protein Expression

Genetic information flows from DNA during transcription to messenger RNA (mRNA) and then...

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