MobiHealth News April 19, 2024
The proof-of-concept study published in Nature Cancer reveals how researchers are using tumor cells to predict whether patients will respond to specific drugs.
Researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), have developed an artificial intelligence tool that predicts whether a patient will respond to cancer treatment drugs using individual tumor cells, according to a study published in Nature Cancer.
Traditional approaches to drug-patient matching focus on bulk sequencing of tumor DNA and RNA. The new AI approach, named PERCEPTION, takes advantage of single-cell RNA sequencing, which provides better resolution data to fine tune predicted drug responses.
The new approach showed promise in two clinical trials for myeloma and breast cancer.
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