Futurity November 11, 2024
In a cell-based study, researchers have forced glioblastoma cells to display immune system targets.
The new strategy could potentially make them visible to immune cells and newly vulnerable to immunotherapies.
Even treated with the most advanced therapies, patients with glioblastoma—an aggressive brain cancer—typically survive less than two years after diagnosis.
Efforts to treat this cancer with the latest immunotherapies have been unsuccessful, likely because glioblastoma cells have few, if any, natural targets for the immune system to attack.
The new strategy involves a combination of two drugs, each already FDA-approved to treat different cancers.
“For patients whose tumors do not naturally produce targets for immunotherapy, we showed there is a way to induce their generation,” says co-senior author Ting Wang,...
Today's Sponsors
Today's Sponsor