Inside Precision Medicine April 23, 2024
A big challenge with the SARS-CoV-2 virus, which causes COVID, is that it regularly generates variants. Now, a new targeted RNA consensus sequencing method (tARC-seq) can accurately determine SARS-CoV-2 mutation frequency and types, both in cell culture and clinical samples, according to researchers at Baylor College of Medicine and collaborating institutions.
The study was published April 22. 2024 in Nature Microbiology. The lead author is Catherine Bradley of Baylor.
According to their work, tARC-seq has already revealed a genetic mechanism affecting SARS-CoV-2 divergence and enabled the team to calculate SARS-CoV-2’s mutation rate. The researchers also used tARC-seq to find new mutations that recapitulated observations revealed by worldwide pandemic viral sequencing data.
“The SARS-CoV-2 virus uses RNA, instead of DNA,...
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