DOTmed December 26, 2025
Keri Stephens

Lung cancer diagnosis just got a powerful upgrade, thanks to a novel radiological model that could dramatically improve the evaluation of nonsolid nodules (NSNs) in lung adenocarcinoma.

NSNs, often seen on CT scans, have long posed challenges in accurate assessment. Determining whether they are preinvasive, minimally invasive, or fully invasive is crucial for treatment decisions.

Published in Radiology, the study analyzed 1,683 patients with confirmed lung adenocarcinoma between January 2012 and June 2024. Researchers reviewed 2,125 NSNs, ranging from 3 mm to 30 mm, evaluating CT characteristics such as size, shape, margin, attenuation, and additional features like lobulation and pleural retraction.

Key findings included the association between larger nodules and increased invasiveness. Additionally, the presence of intranodular vessels was a...

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