Inside Precision Medicine August 14, 2025
Alisa Kirkin

A new non-mechanical optical coherence tomography (OCT) device developed by researchers at the University of Colorado Boulder could reshape how clinicians image delicate structures like the retina in the eye and coronary vessels. By eliminating moving components, this next-generation scanner not only improves reliability but also opens new doors for miniaturized imaging inside the body, including for heart disease detection.

OCT—a non-invasive imaging technique that uses light waves to capture high-resolution, cross-sectional views of tissue, is widely used for diagnosing eye diseases.

The team’s innovation, detailed in Optics Express, uses electrowetting-based liquid lenses to steer light, replacing traditional scanning mirrors. Because the lens shape changes using an applied voltage rather than moving parts, it reduces mechanical failure points and significantly...

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