Futurity July 29, 2024
Yale

New research offers evidence that autoimmunity—in which the body’s immune system targets its own tissues—is a driver in some cases of Long COVID.

Why COVID-19 sometimes leads to Long COVID still confounds doctors, but researchers have several hypotheses to explain its often-debilitating symptoms. These include lingering SARS-CoV-2 remnants, the reactivation of such latent viruses as Epstein-Barr, infection-induced tissue damage, and autoimmunity.

Now, in this new study, when researchers transferred antibodies from patients with Long COVID into healthy mice, the animals began exhibiting symptoms including heightened pain sensation and dizziness. The study is among the first to show a causal link between antibodies and Long COVID symptoms.

“We’re very excited to have a mechanism to study and learn more about so...

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