Healthcare IT News April 28, 2021
Researchers from Cambridge University used data from NHS cancer patient samples sequenced through the 100,000 Genomes Project.
A new algorithm that identifies tumours sensitive to particular immunotherapies could improve the personalisation of cancer therapies.
The MMRDetect clinical algorithm makes it possible to identify tumours that have ‘mismatch repair deficiencies’ and then target treatment to exploit those weaknesses.
It was trained on data from thousands of NHS cancer patient samples sequenced through national whole genome sequencing endeavour, the 100,000 Genomes Project.
The study, led by researchers from the University of Cambridge’s Department of Medical Genetics and MRC Cancer Unit and published today in the journal Nature Cancer, identified nine DNA repair genes that are critical guardians of the human genome.
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