Medical Xpress October 24, 2024
Scientists from Cleveland Clinic and Cornell University have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication.
The computational tool is called PIONEER (Protein-protein InteractiOn iNtErfacE pRediction). Researchers demonstrated PIONEER’s utility by identifying potential drug targets for dozens of cancers and other complex diseases in a recently published Nature Biotechnology article.
Genomic research is key in drug discovery, but it is not always enough on its own, says Feixiong Cheng, Ph.D., study co-lead author and director of Cleveland Clinic’s Genome Center. When it comes to making medications based on genomic data, the average time between discovering a disease-causing gene and entering clinical trials is 10–15 years.
“In theory, making...
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