Medscape March 14, 2025
TOPLINE:
A deep learning–based artificial intelligence (AI) system detected 75.1% of airway nodules, with 0.25 false positives per scan in patients without airway nodules. The system achieved an increased sensitivity of 79% in detecting tumorous nodules, including subtle cases often missed by radiologists.
METHODOLOGY:
- Researchers retrospectively analysed a dataset of 320 chest and chest-abdomen CT scans, including patients with airway nodules (n = 160; median age, 64 years; 58 women) and those without airway nodules (n = 160; median age, 60 years; 80 women).
- An airway nodule was defined as a focal opacity primarily confined within the lumen of the airway (bronchus or trachea).
- Primary cancers were verified through bronchoscopy with biopsy or cytologic testing. The malignancy status of...