Medical Xpress March 25, 2025
Cedars-Sinai investigators have developed a novel artificial intelligence (AI) model, named DYNA, that accurately distinguishes harmful gene variations from harmless ones, potentially enhancing physicians’ ability to diagnose diseases. The new tool could pave the way for more precise personalized medicine and targeted therapies.
In an article published in the journal Nature Machine Intelligence, the team demonstrated that DYNA outperforms existing AI models in accurately predicting which changes in DNA, commonly called mutations, are linked to specific cardiovascular conditions and other disorders.
“In recent years, AI has vastly expanded our ability to detect enormous numbers of genetic variants in ever-larger populations,” said Huixin Zhan, Ph.D., a contributing author of the study from the Department of Computational Biomedicine at Cedars-Sinai. “But up...