AXIOS October 22, 2019
Scientists announced Monday they have developed a “versatile and precise new approach” to targeting and replacing mutated genes that could eventually be used to address roughly 89% of genetic variations known to play a role in human diseases.
Why it matters: The technique, called prime editing, adds a third editing tool for mammalian cells in a manner that lessens the rate of the dangerous off-target deletions or insertions caused by the other types of tools, according to Broad Institute’s David Liu, co-author of the paper published in Nature.
How it works: Liu tells a press conference that with the addition of prime editing, there are now three main ways to edit mammalian cells…
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