Inside Precision Medicine March 26, 2025
Scientists have unveiled a solution to long-standing challenges in molecular data integration for central nervous system (CNS) tumor diagnostics. A Nature Medicine study introduces a nanopore sequencing workflow called Rapid-CNS2 that delivers real-time tumor classification and DNA insights within just 30 minutes during surgery and comprehensive molecular profiling within 24 hours. Complementing it is MNP-Flex, a platform-agnostic methylation classifier that achieved over 99% accuracy across over 78,000 samples worldwide. Together, these tools, developed by researchers at University Hospital Heidelberg, Hopp Children’s Tumor Center (KiTZ), and the German Cancer Research Center (DKFZ), offer advanced speed and accuracy, enabling rapid, actionable insights to guide personalized treatment strategies for CNS tumors.
Advancing brain cancer diagnostics
CNS tumors are notoriously complex, demanding precise and...
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