Mad in America January 1, 2024
Editor’s Note: Over the next several months, Mad in America is publishing a serialized version of Les Ruthven’s book, Much of U.S. Healthcare is Broken: How to Fix It. In this blog, he addresses the scientific literature on antidepressant efficacy and FDA approval. Each Monday, a new section of the book is published, and all chapters are archived here.
A brief review of the scientific literature on depression drug treatment outcome studies.
Some of the following studies appeared in my book Antidepressants: Science, Magic or Marketing,1 and in the next section, I will report on some of the more recent depression treatment outcome studies.
In some published FDA antidepressant placebo-controlled clinical trials, the response rate in terms of symptom reduction...
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