Managed Healthcare Executive February 4, 2024
The success of mRNA vaccines against COVID-19 has led to a surge of mRNA vaccines being developed for other diseases.
Before December 2020, when the FDA authorized the use of two COVID-19 messenger RNA (mRNA) vaccines developed by Pfizer and Moderna, the science behind mRNA vaccines had been researched for over 30 years. After the success of the two pioneering COVID-19 vaccines, these companies have been investigating the mRNA technology for its potential use in vaccines against other infections. These include seasonal influenza (flu), cytomegalovirus (CMV), Zika virus, genital herpes and HIV.
What makes mRNA vaccines different?
mRNA vaccines differ from other types of vaccines in their mechanism of action. Non-mRNA vaccines typically contain attenuated virus, inactivated virus or part...