Medical Xpress January 8, 2026
Mass General Brigham

The worldwide prevalence of obesity has more than doubled in the last three decades, bringing with it an increase in weight-related diseases like diabetes, cardiovascular disease, and cancers. This public health crisis strains global health care systems and economies, but a new study co-led by investigators from Mass General Brigham could inform strategic programs to make GLP-1 medications part of the solution.

Mass General Brigham researchers and collaborators from Washington University School of Medicine in St. Louis and Emory University’s Rollins School of Public Health pooled data from 99 countries and 810,635 adults to determine how many people worldwide may benefit from GLP-1 use.

They found more than one-in-four adults would be eligible for GLP-1s for weight management, with women,...

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