MedPage Today October 9, 2024
Michael DePeau-Wilson

— Secondary analysis suggests lack of clinically meaningful differences in effectiveness

Mindfulness meditation appeared to be similar to escitalopram (Lexapro) in reducing anxiety symptoms at 8 weeks based on several patient- and clinician-reported measures, a secondary analysis of a randomized clinical trial showed.

Among 276 adults who underwent mindfulness-based stress reduction (MBSR) or received escitalopram, between-group differences corresponded to small effect sizes (Cohen d ≤0.20), suggesting a lack of clinically meaningful differences in effectiveness between treatments, wrote Elizabeth A. Hoge, MD, of Georgetown University Medical Center in Washington, D.C., and co-authors in a research letter in JAMA Network Open.

“The bottom line is the two treatments were very similar,” Hoge told MedPage Today. “That confirms our first finding, that meditation...

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