News-Medical.Net November 11, 2024
By harnessing advanced AI, MethylGPT decodes DNA methylation with unprecedented accuracy, offering new paths for age prediction, disease diagnosis, and personalized health interventions.
*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information.
In a recent study posted to the bioRxiv preprint* server, researchers developed a transformer-based foundation model, MethylGPT, for the DNA methylome.
DNA methylation is a type of epigenetic modification that regulates gene expression via methyl-binding proteins and changes in chromatin accessibility. It also helps maintain genomic stability through transposable element repression. DNA methylation has features of an ideal biomarker, and studies have revealed distinct methylation signatures across pathological states,...
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