Behavioral Health Business October 22, 2024
Morgan Gonzales

Medications for opioid use disorder (MOUD) are highly effective, and often life-saving treatments, for patients struggling with opioid use.

Not all medications are created equal, however.

Methadone may help patients stay in treatment for longer compared to buprenorphine and naloxone, according to a new study published in JAMA.

“Methadone was associated with a lower risk of [opioid agonist treatment] (OAT) discontinuation compared with buprenorphine/naloxone,” the study’s authors wrote. “These results add to a growing evidence base consistent with methadone offering greater effectiveness in promoting sustained retention for individuals receiving OAT.”

In a study of over 30,800 patients, those who were treated with methadone spent a median of 66 days in treatment before discontinuing, while those treated with buprenorphine or...

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