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Men face sharper brain aging from obesity and heart risks
News-Medical.Net December 1, 2024
Study reveals how sex-specific risks of obesity and heart health shape brain aging, offering new insights into preventing Alzheimer’s disease.
In a recent study published in the Journal of Neurology, Neurosurgery & Psychiatry, researchers investigated how cardiovascular risk and obesity impact brain volume and whether the apolipoprotein (APOE) genotype affects this relationship in females and males of various ages.
Their findings indicate specific age ranges as the most vulnerable to the impact of obesity and cardiovascular risk on brain volume, with implications for neurodegeneration prevention and the development of Alzheimer’s disease.
Background
Alzheimer’s disease affects approximately 50 million people worldwide, but avenues for treatment, such as anti-amyloid therapies, remain limited. The development of the disease involves the accumulation of toxic...
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