Medical Xpress November 3, 2025
Deborah Stull, University of Pennsylvania

A new large-scale, open data resource from the Perelman School of Medicine and collaborators helps researchers link brain development with mental health disorders.

Mental health disorders such as depression, anxiety, and ADHD affect millions worldwide and contribute significantly to the global burden of disease—impacting individuals’ health and daily lives and placing a substantial strain on social systems and national and global economies.

These conditions often involve differences in brain development, particularly during childhood and adolescence. However, tracking these in relation to psychopathology—the study of —has been limited by the need for large, diverse neuroimaging datasets.

Now, a collaborative team led by Theodore D. Satterthwaite and Golia Shafiei of the Perelman School of Medicine and Michael P....

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