Medical Xpress January 21, 2025
Preeclampsia, intrauterine fetal growth restriction, and other “great obstetrical syndromes” have been linked to disordered placenta development, so understanding the structure and function of this vital organ is critical to detecting pregnancy disorders.
Hemodynamic digital twins are virtual representations of the way blood flows through the body. They have already been proposed to predict cardiovascular disease risk, but collecting measurements of pregnant uteri to inform digital twin models of pregnancy is limited due to safety concerns. By computationally replicating realistic placenta blood flow, Noelia Grande Gutiérrez of Carnegie Mellon University’s Department of Mechanical Engineering is addressing this lack of data.
A breakthrough in the field, her lab has developed a computational model of the basic functional unit of the human...