Medical Xpress November 26, 2024
Subtle signs of Alzheimer’s disease can emerge decades before a diagnosis—often in the form of irregular behaviors that reflect very early stages of brain dysfunction. But until now, identifying and measuring these slight behavioral changes in a scientific way hasn’t been feasible, not even when studying Alzheimer’s in mice.
In a study published in Cell Reports, a team of scientists at Gladstone Institutes used a new video-based machine learning tool to pinpoint otherwise-undetectable signs of early disease in mice that were engineered to mimic key aspects of Alzheimer’s. Their work sheds light on a new strategy for identifying neurological disease earlier than currently possible and tracking how it develops over time.
“We’ve shown the potential of machine learning to revolutionize...