Medical Xpress October 28, 2024
Head and neck cancers have increased significantly over the last 30 years. In Germany, there are about 18,000 to 20,000 new cases of head and neck tumors every year. In particular, the incidence of carcinomas of the middle pharynx has increased, which is associated with the increase in human papillomavirus (HPV) infections.
Using a machine-learning-based method, an interdisciplinary team of researchers led by Sara Wickström at the University of Helsinki, in collaboration with the University of Turku and the Max Planck Institute for Molecular Biomedicine in Germany, has analyzed hundreds of biobank patient samples at the level of individual cells. The new technology combines indicators of cancer cell behavior and the architecture of the tumor and surrounding healthy tissue to...