Medical Xpress September 2, 2024
In a review article, researchers have uncovered compelling evidence that long noncoding RNAs—molecules once dismissed as “junk DNA”—may hold the key to revolutionizing how we diagnose and treat mood disorders.
The study, “Circulating long noncoding RNA: New frontiers in biomarker research for mood disorders,” published in the journal Genomic Psychiatry, reveals that these RNA molecules circulating in blood samples could serve as powerful biomarkers for conditions like major depression and bipolar disorder, potentially leading to more accurate diagnoses and personalized treatments.
“For years, clinicians have struggled with the subjective nature of diagnosing mood disorders,” said Dr. Yogesh Dwivedi, senior author of the study. “Our review shows that lncRNAs detectable in blood samples may offer an objective way to identify these...