News-Medical.Net January 12, 2026
By analyzing millions of patients worldwide, researchers reveal consistent patterns in Long COVID symptoms, offering clinicians a clearer roadmap for diagnosis, referral, and tailored treatment.
In a recent systematic review published in eClinicalMedicine, researchers synthesized data from 64 studies encompassing 2.43 million participants across 20 countries to synthesize existing approaches to Long COVID subtyping and propose a structured, subtype-oriented management framework.
The review summarized how included studies grouped patients or symptoms, leveraging study-level meta-analyses focused primarily on organ systems, based on symptom groupings to examine patterns in symptom clustering.
Review analyses identified four primary methods for categorizing patients: by symptom co-occurrence, affected organ systems, disease severity, and clinical indicators. The analysis highlights fatigue as a central, recurring symptom, affecting 37...
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