Eric Topol February 28, 2024
What we’re learning from 2 new, large population prospective assessments
Two new studies published in the New England Journal of Medicine today address the extent and duration of cognitive deficits after Covid in very large cohorts.
The First Study
In England, in a prospective study nearly 113,000 participants, with or without Covid infections, accepted the invitation to participate and completed a cognitive and memory assessment (see flow chart below from the 800,000 total community of participants) and after 12 weeks, with or without symptom resolution. The cognitive 8-domain assessment (right side of panel below) demonstrated that the impact of Covid was mainly seen on memory, executive function and reasoning. The adverse cognitive impact was worst with the original (ancestral) virus...