MedPage Today April 28, 2024
Mike Bassett

— Survivors with severe loneliness had a 67% increased risk, study finds

Greater feelings of loneliness and social isolation were associated with a higher risk of mortality among cancer survivors, according to a retrospective longitudinal study.

Over the study period of 10 years, cancer survivors with higher loneliness scores on the UCLA Loneliness Scale had higher mortality risk compared with those who had low/no loneliness scores, following a dose-response association:

  • Mild loneliness: adjusted HR 1.19 (95% CI 0.86-1.63)
  • Moderate loneliness: aHR 1.41 (95% CI 1.01-1.96)
  • Severe loneliness: aHR 1.67 (95% CI 1.25-2.23, P=0.004)

The adjusted HR was 1.03 (95% CI 1.01-1.06) when loneliness score was included in multivariable models as a continuous variable, noted Jingxuan Zhao, MPH, of...

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