Bio-IT World February 3, 2021
Contributed Commentary by Zachary Pitluk

Popular opinion is that two big shifts have changed the game for bioinformatics. The first is a technology development—single cell ‘omics—that began just over 10 years ago, the other is a more recent move to a new model of drug discovery that looks to leverage the vast amounts of human genetic data now being generated in support of precision medicine.

Life science research continues to be transformed by single cell ‘omics, notably genomics, transcriptomics, epigenomics, and proteomics at the single-cell level. The technique for examining all the gene products in one cell at one timepoint—single-cell RNA sequencing (scRNA-seq)—was established in the Gurdon Institute at the University of Cambridge, UK, in 2009. Fast forward to 2019, when The Klarman Cell Observatory...

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