Andreessen Horowitz October 9, 2024
“Know your enemy and know yourself and you can fight a hundred battles without disaster.” -Sun Tzu, The Art of War
Cells are the functional unit of life. And yet, they are also the functional units of disease. All human diseases are ultimately caused by dysfunctional cellular function in some fashion—whether by excessive cell growth, hyper- or hypo-activity, altered cell-cell interactions, or changes in the biomolecules a cell produces. And yet, the vast majority of therapeutics approved or in development today act via modulating the activity of individual proteins or other biomolecules within or expressed by the cell. In many cases, this can be an effective strategy. However, given the complexity of cellular function and evolved redundancies in regulatory networks,...
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