Clinical Trials Arena May 29, 2025
Miranda McLaren

Embracing alternative, patient-centric ways of clinical trial delivery could be critical to expanding reach and enhancing data collection in infectious disease trials.

Global immunization programs have successfully eradicated or controlled many infectious diseases throughout history. However, challenges like antimicrobial resistance, climate change, and the potential threat of biological warfare are continuously reshaping the global health landscape. As these factors evolve, new pathogens or mutated strains of existing ones may emerge.

One example is the rapidly spreading Clade 1b mpox strain that emerged from the Democratic Republic of Congo in November 2023, prompting the World Health Organization to declare a “public health emergency of international concern” (PHEIC) in 2024. This was the WHO’s eighth PHEIC of the last two decades[i] and...

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