Medical Xpress January 3, 2025
A paper published in the Journal of Clinical Oncology, titled “Comparative Analysis of Intracranial Response Assessment Criteria in Patients With Melanoma Brain Metastases Treated With Combination Nivolumab + Ipilimumab in CheckMate 204,” examines how different imaging criteria can be used to assess brain tumor responses in patients with melanoma treated with immunotherapy drugs.
The researchers identified one imaging method that was more accurate in predicting survival compared to others. While further work is needed, they say the study is promising and highlights the importance of more consistent imaging standards in clinical trials.
For the study, the researchers looked at different measurements of brain metastases on MRI scans taken over the course of two years or longer for patients in a...