News-Medical.Net January 5, 2025
Researchers uncover how a key human immune protein curbs H5N1 avian flu, but the virus is evolving—could we be on the brink of a new zoonotic threat?
A recent study published in the journal Emerging Infectious Diseases showed that the human immune factor, myxovirus resistance protein 1 (MxA), represses the replication of highly pathogenic avian influenza A (HPAI) viruses of the H5N1 subtype.
HPAI H5N1 clade 2.3.4.4b viruses have increasingly caused mammalian outbreaks over the past few years. In the United States (US), outbreaks have been detected in cows since Spring 2024, leading to viral transmission to farm workers, possibly via contact with contaminated milk or infected cows. This has sparked concerns that these viruses may adapt to humans.
Notably,...
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