Eric Topol January 26, 2025

More Evidence for Our Gut Taking Center Stage for What We Eat

A fascinating new report illuminated a pathway by which receptors in the lining of the gut, working through specific gut bacteria and a key metabolite, ultimately influence the brain’s sugar preference. In this issue of Ground Truths, I’ll review this elegant study and the gut-brain axis, which you’ll now see extending to the gut-liver—brain axis.

Parenthetically, Caity Weaver wrote the cover story in this week’s New York Times Magazine, a hilarious account of her trip to a medical spa in Austria to end her sugar addiction (here is a gift link to her article). A memorable quote: “What I had believed was my own preference was apparently the...

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