Health Affairs November 21, 2024
Jishian Ravinthiran, Aaron S. Kesselheim, Steve Knievel

US taxpayers provide enormous contributions to global biomedical research and drug development, investing $54 billion in 2023. Yet, US patients also face the highest brand-name drug prices in the world. According to a US government report, over the past two decades, the median price for a year of treatment with drugs protected by patents linked to National Institutes of Health (NIH) funding was more than $100,000, and in almost every instance, the price for US residents was higher than for patients in other high-income countries around the world.

High drug prices have important consequences: In recent surveys, about one in three adults report not filling a prescription, cutting pills in half, skipping doses, and/or taking an over-the-counter medication instead of...

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