Health Affairs September 2, 2021
Frederick S. Nolte, Karen L. Kaul

Over a year after the World Health Organization declared the COVID-19 to be a global pandemic, the US should be leading global diagnostic efforts for COVID-19; instead, we have lagged in our response to dangerous viral mutations and variants. The US is home to many of the world’s leading clinical laboratories, test manufacturers, and most prominent thought leaders, but we have trailed many developed countries in ramping up diagnosis and characterization of SARS-CoV-2.

The Centers for Disease Control and Prevention’s (CDC’s) national SARS-CoV-2 genomic surveillance program, established in November 2020, includes genomic sequences from the National SARS-CoV-2 Strain Surveillance program and contracted commercial laboratories. As of May 6, 2021, sequences from 177,044 SARS-CoV-2–positive specimens that were collected between December 20,...

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