Politico October 16, 2024
Erin Schumaker, Carmen Paun, Daniel Payne and Ruth Reader

THE NEXT CURES

Thanks to an award from the Advanced Research Projects Agency for Health, researchers at the Mayo Clinic are hard at work on a new treatment for inflammatory bowel disease.

The clinic is using $42.8 million in ARPA-H funding for a project called “Engage Assess SecretE,” or EASE, which aims to develop a “cell factory,” i.e., an implantable bioelectric device that would trigger genetically engineered cells to create monoclonal antibodies that treat the disease.

Why it matters: IBD, an autoimmune disorder which includes diseases like Crohn’s disease and ulcerative colitis, is an inflammatory digestive condition with symptoms that can include diarrhea, stomach cramps, rectal bleeding, fatigue and weight loss. There’s no cure for the disorder, which ranges in...

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