MedCity News February 23, 2025
Marissa Plescia

Compounded GLP-1s have become more widespread, but are they safe? Some argue that compounding is nothing new, while others believe these drugs are dangerous for patients.

Following Hims & Hers’ Super Bowl ad for its weight loss product, a debate has emerged over the safety of compounded GLP-1s for patients.

Compounded GLP-1s are custom-made by compounding pharmacies and include the same active-ingredient found in branded GLP-1s like Ozempic and Wegovy (semaglutide), but there are some important differences. As the public has become aware of the efficacy of these drugs, demand has soared amidst a shortage of the branded products. Companies of all stripes — digital health companies, medspas, plastic surgery providers and many others — have stepped up to...

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