Medscape April 1, 2025
Racheal Ede

Rates of depression and anxiety were significantly higher in people with chronic pain than in those without pain, results of a new meta-analysis and systematic review showed.

Prevalence was also higher based on pain type, with higher rates of depression and anxiety among those with fibromyalgia than those with osteoarthritis, investigators found.

“The surprising finding is the significant distribution of prevalence in different pain conditions — people with certain types of pain are more vulnerable to depression and anxiety, which is important from a clinical perspective,” lead investigator Rachel Aaron, PhD, assistant professor at Johns Hopkins Medicine, Department of Physical Medicine and Rehabilitation, Baltimore, told Medscape Medical News.

The findings were published online on March 7 in the JAMA Network...

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