Heart health differences in men and women: Tiny RNA molecules play key role, study finds

Medical Xpress February 3, 2025
University of North Carolina at Chapel Hill School of Medicine

There are notable differences between men and women in their susceptibility to many human diseases, including cardiovascular disease. For example, women typically have smaller hearts that pump faster, while men have larger hearts that pump more blood with each heartbeat.

In light of a 2016 report by the National Heart, Lung, and Blood Institute (NHLBI) Working Group on Sex Differences Research in Cardiovascular Disease, researchers have been making massive efforts to understand what, in the underlying biology, predisposes people to sex-specific cardiovascular disease.

Researchers in the laboratories of Frank L. Conlon, Ph.D., professor of biology and genetics, and Bill Marzluff, Ph.D., Kenan Distinguished Professor of Biochemistry and Biophysics, have recently made a large stride in the field, uncovering one of...

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