MedPage Today November 29, 2025
Retrospective studies paint a mixed picture about how weight-loss medications affect risk
GLP-1 receptor agonists are being linked to a long list of benefits besides weight loss and diabetes, as evidence suggests they can lower the risk of conditions ranging from cancer and addiction to suicidal ideation, stroke, and more. But eye health has been an outlier, with research offering conflicting data about whether the medications make certain ocular diseases more or less likely.
What about age-related macular degeneration (AMD), which affects an estimated 19.8 million Americans age 40 and over? Some studies suggest GLP-1 drugs might reduce risk, but there are also hints that they could make progression to advanced AMD more likely. In any case, absolute risk remains...
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