Medical Xpress April 18, 2025
University of Chicago Medical Center

For people living with primary progressive aphasia (PPA), a rare, early-onset neurodegenerative dementia that predominantly affects language abilities, something as simple as ordering their favorite meal at a drive-thru can be a deeply meaningful marker of independence.

Led by experts at the University of Chicago’s Healthy Aging & Alzheimer’s Research Care (HAARC) Center, researchers have published positive results from a clinical trial testing a telehealth intervention designed to help people with PPA maintain their independence for as long as possible.

The findings are published in the journal Alzheimer’s & Dementia.

Designing a rigorous non-drug trial

The Communication Bridge 2 (CB2) trial, which involved 95 “dyads” consisting of individuals with PPA and their primary partners, is the first randomized controlled...

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