Health IT Analytics June 3, 2020
Genetic risk scores can quantify patients’ risk of having a heart attack based on the number of variants they have.
Using genetic risk scores could help identify patients at high risk of heart attack who are not presently identified using traditional clinical methods, according to a study published in the Journal of the American College of Cardiology.
Research has linked genetic variants with a higher risk of having a heart attack, enabling the calculation of polygenic risk scores (PRS) that quantify patients’ inherited susceptibility based on the number of variants they have.
A team from Massachusetts General Hospital and the Broad Institute of Massachusetts Institute of Technology and Harvard applied PRS to 47,108 individuals who were an average age of...