PYMNTS.com January 23, 2026
The U.S. Department of Health and Human Services’ Advanced Research Projects Agency for Health (ARPA-H) is seeking proposals for a multiyear initiative to spur the development and approval of agentic artificial intelligence systems capable of performing clinical tasks previously limited to clinicians.
The program, called Agentic AI-Enabled Cardiovascular Care Transformation (ADVOCATE), aims to establish a pathway toward FDA-authorized agentic AI solutions that go beyond predictive models and toward autonomous, patient-facing assistance in high-risk clinical care settings like cardiovascular disease. Under the plan, selected innovation teams will develop two AI agents designed to support cardiovascular patients and deliver FDA authorization within approximately three years.
Under the program, AI agents would interact with electronic health records, wearable data and patient inputs to...







